Two Harbors Investment plans to issue a $250.0 million jumbo non-agency mortgage-backed security this year, with gradual increases in issuance planned in the coming years, officials at the real estate investment trust said last week. William Roth, a co-chief investment officer at Two Harbors, said there is tremendous opportunity to profit from non-agency MBS issuance – not so much in 2011, but in 2012 through 2014. “Our ability to generate loans to our guidelines and create credit pieces is a runway that could be extremely long,” he said at an investor conference hosted by...